CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15732
Family Name Mitogen-activated protein kinase 14 inhibitor SureCN294394 family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00435764 Functional Category Bioactive
Superfamily Survival motor neuron protein and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 3174

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
Interleukin-12 subunit alpha Inhibitor STA-5326 Family 2 51
HER Inhibitor AC480 Family 4 67
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... 4 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Peptide deformylase, mitochondrial Inhibitor 7h-pyrrolo[3,2-f]... 2 10
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 55
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Mitogen-activated protein kinase 14 inhibitor SureCN3632376 fa... 10 5
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07RDWA fa... 1 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-088VMM fa... 1 12
Mitogen-activated protein kinase kinase kinase kinase 5 and Du... 1 18
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Mitogen-activated protein kinase 10 and Transcription factor A... 4 4
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Aurora kinase A and Cyclin-dependent kinase 1 inhibitor N-[4-[... 12 2
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 3
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Mast/stem cell growth factor receptor Kit and Receptor-type ty... 8 3
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 7-cycl... 1 0
Tyrosine-protein kinase ABL1 and Abelson tyrosine-protein kina... 3 0
TGF-beta receptor type-2 and Vascular endothelial growth facto... 2 1
Mast/stem cell growth factor receptor Kit and Proto-oncogene t... 3 5
Proto-oncogene tyrosine-protein kinase Src and Mast/stem cell ... 4 1
Casein kinase II subunit alpha inhibitor N-[5-[[3-cyano-7-[(1-... 9 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Calcitonin gene-related peptide type 1 receptor ligand N-[2-(7... 16 0
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 6 6
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 7
Epidermal growth factor receptor ligand AGN-PC-073LJS family 4 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-04VNKY family 1 4
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 26 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 12 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 9 0
Mitogen-activated protein kinase 14 inhibitor SureCN2944350 fa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435764 CHEMBL320950 Bioactive SureCN294394

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26822 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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