CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15733
Family Name Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxytryptamine receptor 3E ligand 1-azabicyclo[2.2.2]octan-3-yl indole-1-carboxylate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00435769 Functional Category Bioactive
Superfamily Amg 423 Superfamily
Class Class 147

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
Histamine H1 receptor Ligand Pheniramine Family 10 380
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
C-C chemokine receptor type 2 ligand SureCN5947024 family 11 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7
Histamine H3 receptor ligand AGN-PC-09M6FC family 1 9
Glucose-dependent insulinotropic receptor ligand tert-butyl 4-... 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (2Z)-... 1 0
Indoles Metabolite Ethyl 3-methyl-9H-carbazole-9-carboxylate F... 1 1


External ID

Functional Category

Molecule Name

CFAMM00435769 CHEMBL320963 Bioactive 1-azabicyclo[2.2.2]octan-3-yl indole-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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