CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1574
Family Name Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OU family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00325192 Functional Category Bioactive
Superfamily B1 bradykinin receptor and Muscarinic acetylcholine receptor M2 Binder Superfamily
Class Class 3401

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Substance-P receptor Ligand Orvepitant Family 11 46
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Muscarinic acetylcholine receptor M2 Ligand SCH-211803 Family 3 6
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
C-C chemokine receptor type 5 ligand AC1NUIO8 family 12 11
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-3-methyl-... 3 4
C-C chemokine receptor type 5 ligand AC1L9USC family 3 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor N-[2-... 3 7
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 5
C-C chemokine receptor type 5 ligand AGN-PC-075XOD family 2 0
C-C chemokine receptor type 5 ligand AGN-PC-075XPW family 3 3
Histone deacetylase 6 inhibitor 2-[(E)-2-(4-fluorophenyl)-3-th... 1 1
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 4 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolid... 2 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
C-C chemokine receptor type 5 ligand N-[1-[(3R)-4-[benzenesulf... 3 1
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[2-(3-methy... 1 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
Muscarinic acetylcholine receptor M2 ligand AGN-PC-073RRB family 2 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325193 CHEMBL12354 Bioactive AGN-PC-0745OG
CFAMM00325199 CHEMBL276239 Bioactive AGN-PC-0745PW
CFAMM00325192 CHEMBL12153 Bioactive AGN-PC-0745OU
CFAMM00325191 CHEMBL150845 Bioactive (4-fluoronaphthalen-1-yl)-[4-[4-[1-(4-propan-2-ylsulfonylphenyl)ethylidene]piperidin-1-yl]piperidin-1-yl]methanone
CFAMM00325195 CHEMBL11892 Bioactive AGN-PC-0745OY
CFAMM00325188 CHEMBL150624 Bioactive (4-fluoronaphthalen-1-yl)-[4-[4-[1-(4-propan-2-ylsulfinylphenyl)ethylidene]piperidin-1-yl]piperidin-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27256 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543