CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15743
Family Name Caspase-8 and Caspase-3 inhibitor (3S)-3-[[(2S)-4-methyl-2-[[2-(naphthalen-1-ylamino)acetyl]amino]pentanoyl]amino]-4-oxobutanoic acid family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00435816 Functional Category Bioactive
Superfamily Caspase-3 and Caspase-8 Binder Superfamily
Class Class 348

Cousin Family NamesSeedsMembers
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor SA-6541 Family 4 32
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Pol polyprotein inhibitor Lysine Sulfonamide 11o family 2 6
Mitogen-activated protein kinase 1 and M17 leucyl aminopeptida... 1 21
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
Granzyme B and Caspase-3 inhibitor CHEMBL304368 family 2 1
Neprilysin and Angiotensin-converting enzyme inhibitor 3-[(3S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435813 CHEMBL322631 Bioactive N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-4-methyl-2-[[2-(naphthalen-1-ylamino)acetyl]amino]pentanamide
CFAMM00435816 CHEMBL90224 Bioactive (3S)-3-[[(2S)-4-methyl-2-[[2-(naphthalen-1-ylamino)acetyl]amino]pentanoyl]amino]-4-oxobutanoic acid
CFAMM00435815 CHEMBL90307 Bioactive (3S)-3-[[(2S)-4-methyl-2-[[2-(naphthalen-1-ylamino)-2-oxoacetyl]amino]pentanoyl]amino]-4-oxobutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27070 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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