CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15747
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor 1-[[3-(1,3-benzodioxol-5-ylmethyl)imidazol-4-yl]methyl]-N-(2-methoxyethyl)-N-methyl-4-naphthalen-1-ylpyrrole-3-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00435820 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 16
Class Class 1256

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
TGF-beta receptor type-1 Ligand SB-431542 Family 2 42
Reverse transcriptase Inhibitor Atevirdine Family 4 55
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 3 8
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Nitric oxide synthase, inducible inhibitor SureCN5194847 family 24 48
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Glycogen synthase kinase-3 beta inhibitor 3-imidazo[1,2-a]pyri... 1 1
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X2R ... 1 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435821 CHEMBL322890 Bioactive SureCN7087230
CFAMM00435820 CHEMBL322850 Bioactive 1-[[3-(1,3-benzodioxol-5-ylmethyl)imidazol-4-yl]methyl]-N-(2-methoxyethyl)-N-methyl-4-naphthalen-1-ylpyrrole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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