CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1575
Family Name 5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic receptor ligand 3-amino-2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylsulfanyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-one family
No. of Seeds 7 No. of Other Members 12
Family Centroid CFAMM00325215 Functional Category Bioactive
Superfamily Alpha-1B adrenergic receptor and 5-hydroxytryptamine receptor 1A Binder Superfamily 2
Class Class 2542

Cousin Family NamesSeedsMembers
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 7 23
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 9 22
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 12 10
D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(... 6 14
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 8
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 1 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325220 CHEMBL440599 Bioactive 3-amino-2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylsulfanyl]thieno[2,3-d]pyrimidin-4-one
CFAMM00325204 CHEMBL11900 Bioactive 3-amino-6-ethyl-2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylsulfanyl]thieno[2,3-d]pyrimidin-4-one
CFAMM00325225 CHEMBL275442 Bioactive 3-amino-2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylsulfanyl]-6-propylthieno[2,3-d]pyrimidin-4-one
CFAMM00325215 CHEMBL12028 Bioactive 3-amino-2-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylsulfanyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
CFAMM00325209 CHEMBL12170 Bioactive 2-amino-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylsulfanyl]-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48716 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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