CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15761
Family Name Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluorophenyl)-5-[2-[[(1S)-1-phenylethyl]amino]pyridin-4-yl]-1,3-oxazol-2-yl]-1-methylpiperidin-4-ol family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00435872 Functional Category Bioactive
Superfamily PF-4136309 Superfamily
Class Class 1382

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Adenosine kinase inhibitor 7-[(4aS,7aS)-6-benzyl-3,4,4a,5,7,7a... 2 1
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-... 2 3
Prothrombin inhibitor SureCN6925359 family 6 18
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077D0D family 3 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Cholesteryl ester transfer protein inhibitor AGN-PC-09QM3I family 1 9
Cholesteryl ester transfer protein inhibitor SureCN2837741 family 6 1
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435872 CHEMBL324063 Bioactive 4-[4-(4-fluorophenyl)-5-[2-[[(1S)-1-phenylethyl]amino]pyridin-4-yl]-1,3-oxazol-2-yl]-1-methylpiperidin-4-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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