CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15781
Family Name Prothrombin and Trypsin-1 inhibitor N-[(6-amino-2-methylpyridin-3-yl)methyl]-2-[2-(cyclobutylmethyl)-7-methyl-1,1,5-trioxo-3,4-dihydropyrido[3,4-e][1,2,4]thiadiazin-6-yl]acetamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00435920 Functional Category Bioactive
Superfamily Trypsin-1 and Prothrombin Binder Superfamily 8
Class Class 122

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Corticotropin-releasing factor receptor 1 ligand 5-chloro-1-[(... 1 2
Neutrophil elastase inhibitor 2-[2-oxo-6-phenyl-3-(2-pyridin-2... 1 2
Coagulation factor X inhibitor (6S,8aS)-N-[(6-amino-2-methylpy... 1 1
Beta-secretase 1 inhibitor N-[(2S,3R)-3-amino-4-fluoro-1-pheny... 4 17
Prothrombin inhibitor N-(2-aminoethyl)-2-[5-[[3-(benzylsulfony... 17 5
Prothrombin and Trypsin-1 inhibitor AGN-PC-073JJH family 5 7
Prothrombin and Trypsin-1 inhibitor AGN-PC-073QCQ family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435921 CHEMBL32549 Bioactive N-[(6-amino-2-methylpyridin-3-yl)methyl]-2-[2-(cyclopropylmethyl)-7-methyl-1,1,5-trioxo-3,4-dihydropyrido[3,4-e][1,2,4]thiadiazin-6-yl]acetamide
CFAMM00435920 CHEMBL416033 Bioactive N-[(6-amino-2-methylpyridin-3-yl)methyl]-2-[2-(cyclobutylmethyl)-7-methyl-1,1,5-trioxo-3,4-dihydropyrido[3,4-e][1,2,4]thiadiazin-6-yl]acetamide
CFAMM00435919 CHEMBL34614 Bioactive N-[(6-amino-2-methylpyridin-3-yl)methyl]-2-(2-cyclobutyl-7-methyl-1,1,5-trioxo-3,4-dihydropyrido[3,4-e][1,2,4]thiadiazin-6-yl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27273 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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