CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15790
Family Name Muscarinic acetylcholine receptor M4 and Muscarinic acetylcholine receptor M3 ligand CHEMBL326450 family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00435948 Functional Category Bioactive
Superfamily Platelet-derived growth factor receptor beta and Receptor-type tyrosine-protein kinase FLT3 Binder Superfamily
Class Class 2321

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Synaptic vesicular amine transporter inhibitor indole alkaloi... 3 11
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Hemagglutinin Inhibitor Arbidol Family 1 4
Integrin beta-3 Inhibitor L-756568 Family 8 59
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Platelet-derived growth factor receptor alpha and Platelet-der... 2 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Renin inhibitor SureCN1144364 family 3 15
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Arachidonate 5-lipoxygenase inhibitor AGN-PC-071TED family 9 12
Bile acid receptor ligand SureCN1243717 family 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435948 CHEMBL326450 Bioactive CHEMBL326450

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24530 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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