CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15795
Family Name Pol polyprotein inhibitor (2S)-N-[(2S,3S,4S,5S)-5-[[(2R)-2-[[(2-amino-1,3-thiazol-4-yl)methyl-methylcarbamoyl]amino]-3-methylbutanoyl]amino]-3,4-dihydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-[[methyl(pyridin-2-ylmethyl)carbamoyl]amino]butanamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00435965 Functional Category Bioactive
Superfamily Pol polyprotein and Cathepsin B Binder Superfamily
Class Class 134

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Ritonavir Family 12 49
Renin Inhibitor Zankiren Family 32 50
Pol polyprotein inhibitor AC1LAD48 family 19 5
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 1 1
Histone deacetylase 2 and Histone deacetylase 1 inhibitor benz... 1 10
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 1 0


External ID

Functional Category

Molecule Name

CFAMM00435966 CHEMBL416472 Bioactive Bila 2157 BS
CFAMM00435965 CHEMBL326620 Bioactive (2S)-N-[(2S,3S,4S,5S)-5-[[(2R)-2-[[(2-amino-1,3-thiazol-4-yl)methyl-methylcarbamoyl]amino]-3-methylbutanoyl]amino]-3,4-dihydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-[[methyl(pyridin-2-ylmethyl)carbamoyl]amino]butanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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