CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15797
Family Name Pol polyprotein and Cytochrome P450 3A4 inhibitor (2S)-4-(3a,6a-dihydrothieno[2,3-b]thiophen-5-ylmethyl)-1-[(2S,4R)-2-hydroxy-5-[[(3S,4S)-3-hydroxy-3,4-dihydro-2H-chromen-4-yl]amino]-5-oxo-4-(pyridin-4-ylmethyl)pentyl]-N-(2,2,2-trifluoroethyl)piperazine-2-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00321115 Functional Category Bioactive
Superfamily Pol polyprotein and Cytochrome P450 3A4 Binder Superfamily
Class Class 3351

Cousin Family NamesSeedsMembers
Plasmepsin-2 Inhibitor KNI-10526 Family 8 10
Pol polyprotein inhibitor AC1LARNY family 28 17
Renin and Pepsin A inhibitor [(2S)-1-[[(2R)-1-[[(2S,3R)-1-cycl... 2 2
Pol polyprotein and Cytochrome P450 3A4 inhibitor P3 arylpyrro... 19 1
Pol polyprotein inhibitor pyridylthiophene analog 10 family 3 0
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0


External ID

Functional Category

Molecule Name

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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