CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]-N-[[5-chloro-2-(tetrazol-1-yl)phenyl]methyl]acetamide family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00308196 Functional Category Bioactive
Superfamily Prothrombin and Beta-lactamase Binder Superfamily 2
Class Class 3077

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Prothrombin inhibitor SureCN5855286 family 15 8
Prothrombin inhibitor AGN-PC-09QLAK family 10 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 2 10
Hepatocyte growth factor receptor ligand 5-[(6-phenyl-[1,2,4]t... 6 2
Prothrombin inhibitor 2-[3-cyano-6-(2,2-difluoro-2-pyridin-2-y... 3 0
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 4 15
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Lysosomal Pro-X carboxypeptidase inhibitor [4-[2-(3-chloro-4-f... 5 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (1... 4 0
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2


External ID

Functional Category

Molecule Name

CFAMM00308196 CHEMBL102978 Bioactive 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]-N-[[5-chloro-2-(tetrazol-1-yl)phenyl]methyl]acetamide
CFAMM00308194 CHEMBL319272 Bioactive 2-[(2S)-1-[(2R)-2-amino-3-pyridin-2-ylpropanoyl]pyrrolidin-2-yl]-N-[[5-chloro-2-(tetrazol-1-yl)phenyl]methyl]acetamide
CFAMM00308193 CHEMBL320664 Bioactive 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl]-N-[[5-chloro-2-(1,2,4-triazol-1-yl)phenyl]methyl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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