CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15805
Family Name Mitogen-activated protein kinase 14 inhibitor 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(piperazine-1-carbonyl)-3,4-dihydroquinazolin-2-one family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00435993 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 3154

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 15 24
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 2 2
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00435994 CHEMBL327217 Bioactive AGN-PC-074QFJ
CFAMM00435993 CHEMBL96225 Bioactive 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(piperazine-1-carbonyl)-3,4-dihydroquinazolin-2-one
CFAMM00435992 CHEMBL94444 Bioactive AGN-PC-074QJT

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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