CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15808
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor 4-[4-[benzenesulfonyl(1H-imidazol-5-ylmethyl)amino]phenyl]-N-(2-methylpropyl)piperazine-1-carbothioamide family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00436001 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor Ligand A-315456 Superfamily
Class Class 2000

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... 5 16
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Motilin receptor and Growth hormone secretagogue receptor type... 2 2
Histamine H3 receptor ligand SureCN7853275 family 2 5
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Protein farnesyltransferase alpha subunit and Protein farnesyl... 5 0
Histamine H3 receptor ligand AGN-PC-074FK2 family 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Histamine H3 receptor ligand AGN-PC-074FFM family 1 2
A disintegrin and metalloproteinase with thrombospondin motifs... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436001 CHEMBL32725 Bioactive 4-[4-[benzenesulfonyl(1H-imidazol-5-ylmethyl)amino]phenyl]-N-(2-methylpropyl)piperazine-1-carbothioamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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