CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15810
Family Name Mu-type opioid receptor ligand AGN-PC-00NCMO family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00436009 Functional Category Bioactive
Superfamily Beta-lactamase and Mu-type opioid receptor Binder Superfamily
Class Class 2780

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Histamine H3 receptor Ligand A-317920 Family 9 240
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Granulocyte colony-stimulating factor receptor Ligand N-(2-mor... 1 24
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 9 22
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 15 14
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
Prelamin-A/C inhibitor CHEMBL1330545 family 1 18
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-01ZLS4 family 2 8
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 35
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
Mu-type opioid receptor ligand SureCN9379472 family 1 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Reverse transcriptase/RNaseH inhibitor AC1L9XOT family 2 0
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Translocator protein inhibitor N-[(2,5-dimethoxyphenyl)methyl]... 1 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 4 6
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-methylfuran-3-... 2 1
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 2 1
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 5 6
5-hydroxytryptamine receptor 1A ligand SureCN10513645 family 9 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 1 1
Mu-type opioid receptor ligand AGN-PC-00NCMG family 2 0
Smoothened homolog inhibitor SureCN13591524 family 1 2
Mitogen-activated protein kinase 14 inhibitor SureCN4822166 fa... 1 4
Mitogen-activated protein kinase 14 and Heat shock protein bet... 2 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Huntingtin and Ras-related protein Rab-9A inhibitor CHEMBL1971... 1 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
Sterol O-acyltransferase 1 inhibitor AGN-PC-073SM7 family 1 0
Peroxisome proliferator-activated receptor alpha ligand AGN-PC... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436010 CHEMBL327270 Bioactive AGN-PC-00NCMX
CFAMM00436009 CHEMBL95247 Bioactive AGN-PC-00NCMO
CFAMM00436007 CHEMBL95248 Bioactive AGN-PC-00NCML

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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