CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15816
Family Name Type-1 angiotensin II receptor and Type-2 angiotensin II receptor ligand SureCN9591887 family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00436031 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-2 angiotensin II receptor Binder Superfamily
Class Class 3418

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
Type-1 angiotensin II receptor Ligand Tasosartan Family 10 29
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Smoothened homolog Inhibitor LY2940680 Family 3 18
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Progesterone receptor Ligand GSK-325971A Family 1 13
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-2 angiotensin II receptor Ligand SC-55634 Family 8 5
Tubulin beta chain Inhibitor 2-m-tolyl-1h-[1,8]naphthyridin-4-... 5 2
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Mitogen-activated protein kinase 14 inhibitor SureCN3632376 fa... 10 5
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 30
Smoothened homolog inhibitor SureCN1091571 family 2 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 4
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
Hepatocyte growth factor receptor ligand 5-[[6-(1-methylpyrazo... 4 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
B1 bradykinin receptor ligand N-[4-chloro-2-[[(1R)-1-[4-[3-flu... 5 5
Mast/stem cell growth factor receptor Kit and Epithelial disco... 3 0
Epithelial discoidin domain-containing receptor 1 and Mast/ste... 1 0
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 9 1
Casein kinase II subunit alpha inhibitor CHEMBL401945 family 12 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 35 14
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 4
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 13
Type-1 angiotensin II receptor ligand 2-[[(5-ethylpyrazolo[1,5... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436031 CHEMBL88806 Bioactive SureCN9591887
CFAMM00436030 CHEMBL89164 Bioactive SureCN9590075
CFAMM00436029 CHEMBL327670 Bioactive 2-[propyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyridine-3-carbaldehyde

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42616 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543