CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15833
Family Name Pol polyprotein inhibitor Tertiary Amide deriv. 58 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00436096 Functional Category Bioactive
Superfamily Peptidyl-prolyl cis-trans isomerase FKBP1A and Collagenase 3 Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
RAF proto-oncogene serine/threonine-protein kinase Inhibitor 5... 3 7
Renin Inhibitor CP-305202 Family 9 30
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 13 0
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Histamine H3 receptor ligand 6-[[2-[2-[(2R)-2-methylpyrrolidin... 2 0
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Caspase-1 inhibitor (3S)-3-[[2-[3-(naphthalene-2-carbonylamino... 1 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 4 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 7 2
Platelet-activating factor receptor ligand [(2R,4R)-4-(octadec... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436096 CHEMBL328337 Bioactive Tertiary Amide deriv. 58

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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