CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15841
Family Name Prostaglandin G/H synthase 2 inhibitor [4-[3-(4-methylsulfonylphenyl)-5-oxo-2H-furan-4-yl]phenyl] acetate family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00436130 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 inhibitor [4-[3-(4-methylsulfonylphenyl)-5-oxo-2H-furan-4-yl]phenyl] acetate Superfamily
Class Class 3483

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Collagenase 3 and Interstitial collagenase Inhibitor 3-(4-meth... 12 76
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(3-... 2 16
Prostaglandin G/H synthase 2 Inhibitor Furan-3-yl(4-(methylsul... 2 4
Hormone-sensitive lipase Inhibitor 2-(3-methoxybenzylthio)-2-p... 1 19
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 33
Cysteinyl leukotriene receptor 1 ligand 4-[(E)-1-carboxy-6-[4-... 2 9
72 kDa type IV collagenase and Stromelysin-1 inhibitor 3-cyclo... 5 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 2
Seed linoleate 13S-lipoxygenase-1 and Prostaglandin G/H syntha... 1 1
2-(2,5-dimethoxyphenyl)sulfonyl-3,6-dimethoxybenzoate NP ZINC0... 1 3


External ID

Functional Category

Molecule Name

CFAMM00436131 CHEMBL93024 Bioactive [3-[3-(4-methylsulfonylphenyl)-5-oxo-2H-furan-4-yl]phenyl] acetate
CFAMM00436124 CHEMBL328616 Bioactive [2-[3-(4-methylsulfonylphenyl)-5-oxo-2H-furan-4-yl]phenyl] acetate
CFAMM00436130 CHEMBL93372 Bioactive [4-[3-(4-methylsulfonylphenyl)-5-oxo-2H-furan-4-yl]phenyl] acetate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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