CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1590
Family Name Platelet-activating factor receptor ligand SureCN9383514 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00325401 Functional Category Bioactive
Superfamily Platelet-activating factor receptor and Glucosylceramidase Binder Superfamily
Class Class 2257

Cousin Family NamesSeedsMembers
Benzodiazepine receptor Ligand Midazolam Family 5 160
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
HCV NS4B protein Inhibitor Clemizole Family 2 43
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
Corticotropin-releasing factor receptor 1 ligand SureCN5395386... 6 5
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 7 7
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 3 5
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... 3 21
Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dich... 3 10
Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dich... 2 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
D(4) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Urokinase plasminogen activator surface receptor ligand 3-(1H-... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 4
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 2 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
Nociceptin receptor and Potassium voltage-gated channel subfam... 5 2
Mitogen-activated protein kinase 14 inhibitor 5-[2-(2,6-dichlo... 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Coagulation factor X inhibitor SureCN1652469 family 2 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00FF1P... 1 3
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-[2-... 9 0
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Lysosomal Pro-X carboxypeptidase inhibitor 1-[6-[(2S)-2-(5,6-d... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325402 CHEMBL119660 Bioactive SureCN9385809
CFAMM00325401 CHEMBL119439 Bioactive SureCN9383514
CFAMM00325400 CHEMBL177351 Bioactive SureCN9383459
CFAMM00325403 CHEMBL119412 Bioactive 7,8-dichloro-4-[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenyl]-1,3-dihydro-1,5-benzodiazepine-2-thione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26858 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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