CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15909
Family Name 5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic receptor ligand 2-[[4-(1H-benzimidazol-4-yl)piperazin-1-yl]methyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00436341 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Alpha-1B adrenergic receptor Binder Superfamily
Class Class 3587

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Histamine H1 receptor Ligand Mizolastine Family 14 603
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Histamine H4 receptor ligand SureCN602132 family 1 8
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 2
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1H-benzimidazo... 3 5
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1-phenylimidaz... 2 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 1
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 5 0
Melanin-concentrating hormone receptor 1 ligand SureCN3832854 ... 3 2
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloroph... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436341 CHEMBL33258 Bioactive 2-[[4-(1H-benzimidazol-4-yl)piperazin-1-yl]methyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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