CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15918
Family Name Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-6,7-dihydro-5H-1-benzothiophen-4-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00436362 Functional Category Bioactive
Superfamily Prolyl endopeptidase and Histamine H3 receptor Binder Superfamily
Class Class 3814

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-612... 1 11
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-5-[4-(oxan-4-... 21 7
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OU family 6 6
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-[4-... 1 1
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(2-... 5 1
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Melanin-concentrating hormone receptor 1 ligand N-methyl-4-(4-... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Coagulation factor X inhibitor 5-chloro-N-[(1R,2S)-2-[[4-[1-(p... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
Prolyl endopeptidase inhibitor [(2S)-2-(pyrrolidine-1-carbonyl... 2 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-ami... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 13


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436362 CHEMBL333621 Bioactive 2-[2-oxo-2-[(2S)-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-6,7-dihydro-5H-1-benzothiophen-4-one
CFAMM00436365 CHEMBL382986 Bioactive SureCN5220693

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43090 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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