CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1592
Family Name Gonadotropin-releasing hormone receptor ligand AGN-PC-034WF4 family
No. of Seeds 8 No. of Other Members 23
Family Centroid CFAMM00325440 Functional Category Bioactive
Superfamily Gonadotropin-releasing hormone receptor ligand AGN-PC-034WF4 Superfamily
Class Class 2579

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
Smoothened homolog Inhibitor LDE225 Family 3 76
MK-6096 family 3 69
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
Metabotropic glutamate receptor 5 ligand AGN-PC-09QLD2 family 1 2
Glucose-dependent insulinotropic receptor and Potassium voltag... 4 0
Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin... 4 1
MAP kinase-activated protein kinase 2 inhibitor 4-[5-[4-(4-pip... 1 11
Gonadotropin-releasing hormone receptor and Voltage-dependent ... 2 0
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
MAP kinase-activated protein kinase 2 inhibitor 4-[5-[[2-(2-me... 3 4
MAP kinase-activated protein kinase 2 inhibitor 4-[4-oxo-8-pip... 4 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 19 2
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M5I2 fa... 1 3
Motilin receptor ligand SureCN13392247 family 1 0
Diacylglycerol O-acyltransferase 1 inhibitor 2-[[4-[5-[(3-meth... 2 6


External ID

Functional Category

Molecule Name

CFAMM00325438 CHEMBL121145 Bioactive N-[[3-[[[2-[[(2S)-oxolan-2-yl]methylamino]pyrimidin-4-yl]amino]methyl]phenyl]methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide
CFAMM00325410 CHEMBL333461 Bioactive N-[[3-[[4-(oxolan-2-ylmethylamino)pyrimidin-2-yl]amino]cyclohexyl]methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide
CFAMM00325437 CHEMBL333574 Bioactive AGN-PC-034XT6
CFAMM00325409 CHEMBL120164 Bioactive N-[[3-[[[4-[[(2R)-oxolan-2-yl]methylamino]pyrimidin-2-yl]amino]methyl]phenyl]methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide
CFAMM00325428 CHEMBL121367 Bioactive AGN-PC-034XS7
CFAMM00325426 CHEMBL333345 Bioactive SureCN5836007
CFAMM00325440 CHEMBL119546 Bioactive AGN-PC-034WF4
CFAMM00325439 CHEMBL124056 Bioactive N-[[3-[[[4-[[(2S)-oxolan-2-yl]methylamino]pyrimidin-2-yl]amino]methyl]phenyl]methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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