CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1596
Family Name Leukotriene A-4 hydrolase inhibitor 3-[3-(4-benzylphenoxy)propyl-methylamino]-N-methylsulfonylpropanamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00325469 Functional Category Bioactive
Superfamily Collagenase 3 and 72 kDa type IV collagenase Binder Superfamily 5
Class Class 3248

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 10 15
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Leukotriene A-4 hydrolase inhibitor SureCN2108222 family 3 9
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 12 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Bone morphogenetic protein 1 inhibitor N-hydroxy-3-[[4-[(Z)-N'... 1 1
Lysosomal alpha-glucosidase inhibitor MLS000587024 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325469 CHEMBL119683 Bioactive 3-[3-(4-benzylphenoxy)propyl-methylamino]-N-methylsulfonylpropanamide
CFAMM00325468 CHEMBL323686 Bioactive SureCN2108981

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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