CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15987
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor 4-[2-[bis(4-fluorophenyl)methoxy]ethyl]-1-[(4-chlorophenyl)methyl]piperidine family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00237366 Functional Category Bioactive
Superfamily Histamine H1 receptor Ligand Clemastine Superfamily
Class Class 225

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Histamine H1 receptor Ligand Clemastine Family 5 76
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Pitolisant family 4 24
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
Substance-P receptor ligand 4-[[3,5-bis(trifluoromethyl)phenyl... 2 1
Substance-P receptor ligand 1-[[(1R,2R,3S)-3-[[3,5-bis(trifluo... 4 3
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Substance-P receptor ligand AGN-PC-03NGZP family 3 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Substance-P receptor ligand SureCN8415737 family 3 4
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 0
C-C chemokine receptor type 5 ligand AC1LAKN8 family 4 5
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Substance-P receptor ligand AGN-PC-02K8GG family 1 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Cannabinoid receptor 2 ligand SureCN4472215 family 2 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0793IB... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436572 CHEMBL539567 Bioactive AGN-PC-07C2E0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26832 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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