CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15997
Family Name Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand SureCN9199596 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00436614 Functional Category Bioactive
Superfamily Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Binder Superfamily 2
Class Class 2290

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxepin Family 8 89
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Muscarinic acetylcholine receptor M1 Ligand Fesoterodine Fumar... 1 0
Cholesteryl ester transfer protein Inhibitor Anacetrapib Family 3 63
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
Integrin alpha-4 Inhibitor Firategrast Family 3 93
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Interleukin-1 beta Inhibitor Diacerein Family 3 77
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 8 12
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Histamine H1 receptor ligand SureCN5064818 family 4 9
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 12 0
Prostaglandin E2 receptor EP4 subtype ligand 4-[(1S)-1-[[2-(tr... 2 1
Prostaglandin D2 receptor 2 and Chemoattractant receptor-homol... 1 1
Free fatty acid receptor 1 ligand 3-[4-[[3-[2,6-dimethyl-4-[3-... 1 0
Estrogen receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[4... 1 2
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Histamine H3 receptor and D(3) dopamine receptor ligand AGN-PC... 1 0
Free fatty acid receptor 1 ligand (3R,4R)-3-[4-(3,4-dimethylph... 4 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 2 1
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor SureCN807991... 1 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 7
Putative NP ZINC04061066 Family 18 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436615 CHEMBL49866 Bioactive SureCN7987971
CFAMM00436614 CHEMBL339479 Bioactive SureCN9199596

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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