CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1601
Family Name Prothrombin inhibitor (2S)-N-[(4-carbamimidoylthiophen-2-yl)methyl]-1-[(2R)-3,3-diphenyl-2-(sulfamoylamino)propanoyl]pyrrolidine-2-carboxamide family
No. of Seeds 12 No. of Other Members 9
Family Centroid CFAMM00325506 Functional Category Bioactive
Superfamily Prothrombin and Cationic trypsin Binder Superfamily 2
Class Class 3332

Cousin Family NamesSeedsMembers
B2 bradykinin receptor Ligand Icatibant Family 9 27
Prothrombin Inhibitor LB30812 Family 12 36
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Prothrombin inhibitor 2-[[(2R)-1-[(2S)-2-[(4-carbamimidoylthio... 9 4
Prothrombin and Trypsin-1 inhibitor 2-[3-(benzylsulfonylamino)... 2 2
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Prothrombin and Cationic trypsin inhibitor (2S)-3-(5-carbamimi... 2 0
B2 bradykinin receptor ligand CHEMBL2028837 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325512 CHEMBL331742 Bioactive (2S)-N-[(5-carbamimidoylthiophen-2-yl)methyl]-1-[(2R)-3,3-diphenyl-2-(sulfamoylamino)propanoyl]pyrrolidine-2-carboxamide
CFAMM00325505 CHEMBL333969 Bioactive methyl N-[(2R)-1-[(2S)-2-[(4-carbamimidoylthiophen-2-yl)methylcarbamoyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]carbamate
CFAMM00325518 CHEMBL1795037 Bioactive benzenecarboximidamide;(2S)-N-[(5-carbamimidoylthiophen-2-yl)methyl]-1-[(2R)-2-(methanesulfonamido)-3,3-diphenylpropanoyl]pyrrolidine-2-carboxamide
CFAMM00325511 CHEMBL120079 Bioactive 3-[[(2R)-1-[(2S)-2-[(5-carbamimidoylthiophen-2-yl)methylcarbamoyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]amino]propanoic acid
CFAMM00325516 CHEMBL332764 Bioactive (2S)-N-[(5-carbamimidoylthiophen-3-yl)methyl]-1-[(2R)-3,3-diphenyl-2-(sulfamoylamino)propanoyl]pyrrolidine-2-carboxamide
CFAMM00325507 CHEMBL119877 Bioactive methyl N-[(2R)-1-[(2S)-2-[(5-carbamimidoylthiophen-2-yl)methylcarbamoyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]carbamate
CFAMM00325520 CHEMBL121379 Bioactive methyl N-[(2R)-1-[(2S)-2-[(5-carbamimidoylthiophen-3-yl)methylcarbamoyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]carbamate
CFAMM00325506 CHEMBL122410 Bioactive (2S)-N-[(4-carbamimidoylthiophen-2-yl)methyl]-1-[(2R)-3,3-diphenyl-2-(sulfamoylamino)propanoyl]pyrrolidine-2-carboxamide
CFAMM00325519 CHEMBL332819 Bioactive 2-[[(2R)-1-[(2S)-2-[(5-carbamimidoylthiophen-3-yl)methylcarbamoyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]amino]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48694 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543