CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16015
Family Name P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-(3-methoxy-2-methylphenyl)acetamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00436678 Functional Category Bioactive
Superfamily Beta adrenergic receptor ligand quinolone derivative Carteolol Superfamily
Class Class 61

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
D(2) dopamine receptor Ligand Aplindore Fumarate Family 2 30
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Fatty-acid amide hydrolase 1 Inhibitor Phenylcarbamic Acid Bip... 3 7
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Sodium-dependent serotonin transporter and D(2) dopamine recep... 4 2
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family 3 3
Trace amine-associated receptor 1 ligand EPPTB family 4 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 3 3
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 3
Urokinase-type plasminogen activator and Trypsin-1 inhibitor A... 1 6
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 5 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 12
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 2
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
Trace amine-associated receptor 1 ligand ZINC07609882 family 2 0
Histone deacetylase 1 and Histone deacetylase 2 inhibitor Sure... 2 0
N-(4-acetamidophenyl)-2-(2,2-dimethyl-3,4-dihydrochromen-6-yl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436679 CHEMBL424451 Bioactive 2-(1-adamantyl)-N-(5-methoxy-2-methylphenyl)acetamide
CFAMM00436678 CHEMBL341226 Bioactive 2-(1-adamantyl)-N-(3-methoxy-2-methylphenyl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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