CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16020
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor 2-[[3-[2-[bis(4-fluorophenyl)methoxy]ethyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methyl]-1H-indole family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00171625 Functional Category Bioactive
Superfamily Grt 6005/06 Superfamily
Class Class 1304

Cousin Family NamesSeedsMembers
Food vacuoles Inhibitor Mefloquine Family 2 25
Grt 6005/06 family 4 22
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
D(2) dopamine receptor Ligand SLV-314 Family 19 69
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
D(1B) dopamine receptor and D(2) dopamine receptor Ligand Flut... 1 6
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 18 17
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Glucocorticoid receptor ligand SureCN5650626 family 17 25
Glucocorticoid receptor ligand AGN-PC-0A9RHA family 1 2
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
Transporter and Sodium-dependent serotonin transporter inhibit... 2 1
5-hydroxytryptamine receptor 2A ligand (3R,4R)-3-(2-phenyl-1H-... 1 18
D(1A) dopamine receptor and D(3) dopamine receptor ligand RU-2... 3 4
CGMP-dependent protein kinase inhibitor AGN-PC-0761UG family 1 2
Protein kinase C theta type and Protein kinase C delta type in... 10 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436700 CHEMBL540371 Bioactive AGN-PC-07C2S1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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