CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16048
Family Name Dihydrofolate reductase and Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor AC1NRRAZ family
No. of Seeds 3 No. of Other Members 21
Family Centroid CFAMM00436592 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Bifunctional dihydrofolate reductase-thymidylate synthase Binder Superfamily 3
Class Class 1208

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 5 12
Peptide deformylase, mitochondrial Inhibitor Brodimoprim-4,6-d... 9 1
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 2 3
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Leukotriene B4 receptor 1 ligand AGN-PC-07ZF09 family 3 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 6
Dihydrofolate reductase inhibitor (E)-3-[5-[(2,4-diaminopyrimi... 3 2
Metabotropic glutamate receptor 5 ligand AGN-PC-09QLD2 family 1 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
Xanthine dehydrogenase/oxidase inhibitor 4-[[4-(2-aminopyrimid... 3 16
Cathepsin K and Cathepsin L1 inhibitor 2-Cyano-pyrimidine, 17a... 5 8
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 5
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[3,4-di... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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