CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16065
Family Name Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydroxy-4-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methyl-[1,2]oxazolo[5,4-b]pyridine-5-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00436881 Functional Category Bioactive
Superfamily Collagenase 3 and Matrix metalloproteinase-9 Binder Superfamily 3
Class Class 979

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 15 18
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 6 2
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 1 2
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00436883 CHEMBL36309 Bioactive 4-[(4-but-2-ynoxyphenyl)sulfonyl-methylamino]-N-hydroxy-3-methyl-[1,2]oxazolo[5,4-b]pyridine-5-carboxamide
CFAMM00436881 CHEMBL34418 Bioactive N-hydroxy-4-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]-3-methyl-[1,2]oxazolo[5,4-b]pyridine-5-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27399 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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