CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM161
Family Name Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phenyl-4-[[(1R)-1-phenylpropyl]carbamoyl]quinolin-3-yl]oxyacetic acid family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00182846 Functional Category Bioactive
Superfamily Substance-K receptor and Neuromedin-K receptor Binder Superfamily
Class Class 656

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Cysteinyl leukotriene receptor 1 Ligand Pranlukast Family 21 72
Egl nine homolog 2 Inhibitor FG-4592 Family 1 4
Neuromedin-K receptor Ligand Talnetant Family 3 49
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Acetylcholinesterase and Muscarinic acetylcholine receptor M2 ... 2 7
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Cysteinyl leukotriene receptor 1 ligand 4-[(2S)-2-[[7-(quinoli... 6 15
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Renin inhibitor AGN-PC-09M9MJ family 2 23
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
Cysteinyl leukotriene receptor 1 ligand SureCN9053715 family 2 11
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 16 5
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Pol polyprotein inhibitor (2S)-N-[4-[cyclopentyloxy-(4-methoxy... 1 0
NS5B protein inhibitor AC1O5AET family 3 1
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Cholinesterase and Acetylcholinesterase inhibitor 4-oxo-N-[9-(... 11 13
Prostaglandin D2 receptor 2 ligand 2-[1-[4-[(4-methoxybenzoyl)... 2 2
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Plasmepsin-2 and Cathepsin D inhibitor 4-[4-[[(2S,3S)-1-[[(3S,... 3 0
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Sonic hedgehog protein inhibitor 3-methoxy-1-methyl-4-oxo-5-ph... 5 3
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Cholinesterase and Acetylcholinesterase inhibitor 6-[4-[2-fluo... 17 0
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 19 11
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[(1-acetylpiperidin-4... 58 15
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3
Prothrombin inhibitor AGN-PC-074I2Z family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308268 CHEMBL2113680 Bioactive ethyl 2-[2-phenyl-4-[[(1S)-1-phenylpropyl]carbamoyl]quinolin-3-yl]oxyacetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26410 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543