CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16115
Family Name Neuronal acetylcholine receptor subunit alpha-4 and Neuronal acetylcholine receptor subunit beta-2 ligand AGN-PC-0754FM family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00437068 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit beta-2 and Neuronal acetylcholine receptor subunit alpha-3 Binder Superfamily 2
Class Class 553

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
Transient receptor potential cation channel subfamily V member... 16 295
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 23 63
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Macrophage migration inhibitory factor Inhibitor 1-(2-chloroph... 2 22
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Reverse transcriptase Inhibitor PT-109 Family 6 7
5-hydroxytryptamine receptor 1A and D(1A) dopamine receptor li... 2 3
Acetylcholine receptor subunit delta ligand Guanidine, N-[(6-c... 2 15
Acetylcholine receptor subunit delta and Neuronal acetylcholin... 3 5
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 8 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 1
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 2 1
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 2 4
D(4) dopamine receptor and D(2) dopamine receptor ligand (E)-1... 1 2
Neuropeptide Y receptor type 5 ligand SureCN4464548 family 17 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 3
Neuronal acetylcholine receptor subunit alpha-3 and Neuronal a... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437067 CHEMBL349623 Bioactive 2-chloro-5-[(1-methyl-4,5-dihydroimidazol-2-yl)methyl]pyridine
CFAMM00437068 CHEMBL349250 Bioactive AGN-PC-0754FM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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