CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16152
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A inhibitor 224789-21-3 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00048942 Functional Category Bioactive
Superfamily cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Vardenafil Superfamily
Class Class 253

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Vardena... 3 39
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Sildena... 17 40
Adenosine receptor A2a Ligand KW-6002 Family 18 195
GP-531 family 1 33
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 6 14
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 17 3
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Prelamin-A/C inhibitor CHEMBL1501476 family 1 2
Survival motor neuron protein and Microtubule-associated prote... 2 14
Extracellular calcium-sensing receptor ligand (5R)-N-[3-(4-eth... 6 7
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor 2-[4-[... 2 6
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 13 2
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 1 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 10 0
Adenosine receptor A1 and Adenosine receptor A2b ligand (2,5-d... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor N-[3-(1... 26 6
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiest... 7 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
P2X purinoceptor 7 inhibitor (7R)-1-[(3,4-difluorophenyl)methy... 1 0
Beta-lactamase and Retinal dehydrogenase 1 inhibitor CHEMBL135... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437178 CHEMBL353248 Bioactive 2-(2-propoxyphenyl)-9-propyl-3H-purin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26384 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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