CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16173
Family Name Pol polyprotein inhibitor AC1LACBC family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00437292 Functional Category Bioactive
Superfamily Renin and Pol polyprotein Binder Superfamily
Class Class 168

Cousin Family NamesSeedsMembers
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Flovagatran family 12 546
Renin Inhibitor CP-80794 Family 16 112
Neuromedin-K receptor Ligand Senktide Family 15 22
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cruzipain Inhibitor WRR-204 Family 18 35
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Plasmepsin-2 Inhibitor KNI-10232 Family 8 36
Beta-secretase 1 Inhibitor KMI-172 Family 3 0
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Protein farnesyltransferase subunit beta Inhibitor L-739750 Fa... 4 0
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Pol polyprotein inhibitor 169168-45-0 family 7 11
Pol polyprotein inhibitor 169273-51-2 family 10 0
Pol polyprotein inhibitor AC1LA3TO family 8 0
Renin inhibitor (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[... 12 1
Renin inhibitor (2S,4S,5S)-N-(4-aminobutyl)-6-cyclohexyl-4-hyd... 32 2
Pol polyprotein inhibitor penicillin deriv. 49 family 3 19
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Pol polyprotein inhibitor penicillin deriv. 69 family 1 1
Beta-secretase 1 and Cathepsin D inhibitor (1R,3S)-N-[(2S,3S)-... 2 25
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Renin and Cathepsin D inhibitor (2S)-N-[(2S,3R,4S)-1-cyclohexy... 13 2
Cathepsin B and Calpain-2 catalytic subunit inhibitor AGN-PC-0... 2 2
Renin and Cathepsin D inhibitor (3S)-4-[[6-acetamido-2-[[3-nap... 6 26
Pol polyprotein inhibitor benzyl N-[(2S,3R)-4-[(3aR,6S,7aS)-6-... 3 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-cycl... 1 6
Pol polyprotein inhibitor Sulfone deriv. 31 family 15 4
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1
Pol polyprotein inhibitor AC1LADQG family 7 1
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 3 3
Beta-secretase 1 inhibitor (2S)-2-[(3R)-3-acetamido-3-(2-methy... 3 0
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 11
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 13 3
Beta-secretase 1 and Cathepsin B inhibitor SureCN4666465 family 9 4
Cathepsin E and Renin inhibitor (2S)-N-[2-[[(2S,3S,5S)-1-cyclo... 4 0
Beta-secretase 1 and Cathepsin B inhibitor 3-chloro-N-[(2S)-1-... 2 0
Renin and Cathepsin D inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-cy... 2 0
Renin inhibitor (1R,2R,3S)-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl... 5 0
Pol polyprotein inhibitor AC1LAH8S family 11 1
Pol polyprotein inhibitor AC1L9R8I family 1 0
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0
Pol polyprotein inhibitor AC1LA3V9 family 2 1
Pol polyprotein inhibitor Diol-Based HIV-1 protease inhibitor ... 1 0
Renin inhibitor MRM-HFA-CYM-CPY family 1 0
Pol polyprotein inhibitor (2R,4S)-N-[(2S)-3-[(3S,4aS,8aS)-3-(t... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437292 CHEMBL355316 Bioactive AC1LACBC
CFAMM00437291 CHEMBL99081 Bioactive 173918-20-2

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543