CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16182
Family Name Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-[[1-[[(2S)-3-methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-pyridin-3-ylpropanoic acid family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00232630 Functional Category Bioactive
Superfamily Integrin beta-3 Inhibitor Elarofiban Superfamily
Class Class 134

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Atazanavir Family 16 58
Substance-P receptor Ligand GSK424887 Family 8 184
CP-18770 family 6 27
FK506-binding protein 1A Inhibitor Gpi-1046 Family 4 10
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Angiotensin-converting enzyme and Endothelin-converting enzyme... 2 10
Endothelin B receptor Ligand IRL-2500 Family 34 87
Endothelin-converting enzyme 1 inhibitor 2-[[1-[[(2S)-4-methyl... 2 8
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 17 14
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Integrin beta-3 and Integrin alpha-IIb inhibitor 3-[[1-(3-pipe... 3 0
Prothrombin and Tissue-type plasminogen activator inhibitor 2-... 4 5
Prothrombin inhibitor 1o0d family 2 0
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2S,4R)... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
Probable G-protein coupled receptor 142 ligand (2S)-2-[[(2R)-o... 1 0
Thromboxane A2 receptor ligand SureCN8058805 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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