CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16200
Family Name Proline--tRNA ligase, cytoplasmic and Bifunctional glutamate/proline--tRNA ligase inhibitor 2-(4-bromophenyl)-6-chloro-8-methylquinoline-4-carboxylic acid family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00437368 Functional Category Bioactive
Superfamily Prelamin-A/C and Survival motor neuron protein Binder Superfamily
Class Class 3182

Cousin Family NamesSeedsMembers
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Cysteinyl leukotriene receptor 1 ligand (2S)-3-[(1S)-3-(2-acet... 6 1
NS5B protein inhibitor AC1NQMYP family 5 0
Tyrosine-protein phosphatase non-receptor type 1 and Receptor-... 1 0
Capsid scaffolding protein inhibitor 4-[[[5-[(E)-2-(7-chloroqu... 1 1
Nuclear receptor subfamily 4 group A member 1 ligand 5-Chloro-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00437368 CHEMBL357355 Bioactive 2-(4-bromophenyl)-6-chloro-8-methylquinoline-4-carboxylic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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