CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16210
Family Name 5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine receptor 3B ligand AGN-PC-075OMY family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00437389 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine receptor 3B Binder Superfamily
Class Class 4020

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 3 15
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Hepatocyte growth factor receptor Ligand 1-benzyl-1h-pyrrolo[3... 2 16
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Metabotropic glutamate receptor 5 Ligand 5-(2-methylquinolin-7... 4 3
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Progesterone receptor and Androgen receptor ligand 5-[4-[(Z)-C... 2 5
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
5-hydroxytryptamine receptor 6 ligand 5-[3-(2-aminoethyl)indol... 1 0
5-hydroxytryptamine receptor 1D ligand AGN-PC-01NTBS family 1 1
5-hydroxytryptamine receptor 7 ligand 6-bromo-1-[2-[4-(cyclopr... 2 4
Thromboxane-A synthase inhibitor AGN-PC-07BYVF family 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437389 CHEMBL358412 Bioactive AGN-PC-075OMY

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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