CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16215
Family Name Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino-2-phenylethyl]-1-[[2-fluoro-6-(2-hydroxyethylsulfonyl)phenyl]methyl]-5-(2-fluoro-3-methoxyphenyl)pyrimidine-2,4-dione family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00437401 Functional Category Bioactive
Superfamily Muscleblind-like protein 1 and Inositol monophosphatase 1 Binder Superfamily
Class Class 854

Cousin Family NamesSeedsMembers
Elagolix family 43 98
Gonadotropin-releasing hormone receptor ligand SureCN6662468 f... 2 0


External ID

Functional Category

Molecule Name

CFAMM00437401 CHEMBL359558 Bioactive 3-[(2R)-2-amino-2-phenylethyl]-1-[[2-fluoro-6-(2-hydroxyethylsulfonyl)phenyl]methyl]-5-(2-fluoro-3-methoxyphenyl)pyrimidine-2,4-dione
CFAMM00437400 CHEMBL453167 Bioactive 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[(2-fluoro-6-methylsulfonylphenyl)methyl]-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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