CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16237
Family Name Melanin-concentrating hormone receptor 1 ligand SureCN13451707 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00437486 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and cAMP-specific 3',5'-cyclic phosphodiesterase 4D Binder Superfamily
Class Class 3520

Cousin Family NamesSeedsMembers
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Phospholipase D1 Inhibitor Halopemide Family 17 111
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C8 inhib... 6 5
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 2 2
Melanin-concentrating hormone receptor 1 ligand SureCN3845324 ... 7 4
Melanin-concentrating hormone receptor 1 ligand 1-[4-(3-cyanop... 4 9
Melanin-concentrating hormone receptor 1 ligand SureCN14265737... 2 0
Melanin-concentrating hormone receptor 1 ligand N-[2-[4-(3-cya... 3 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand SureCN14265866... 11 2
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 2
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00CYMY ... 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Melanin-concentrating hormone receptor 1 ligand 3-chloro-5-[4-... 2 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 4 0
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Mitogen-activated protein kinase 14 inhibitor 5-(2-chloro-4-fl... 3 0
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 1 6
Melanin-concentrating hormone receptor 1 ligand 1-[4-chloro-3-... 1 1
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 2 4
Neuropeptide Y receptor type 5 ligand SureCN6214451 family 3 1
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
Cannabinoid receptor 1 ligand SureCN14463736 family 2 0
Glucagon receptor and Adenylate cyclase type 1 ligand AGN-PC-0... 1 0
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
C-X-C chemokine receptor type 3 ligand N-[3-[7-chloro-3-[2-(4-... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Melanin-concentrating hormone receptor 1 ligand N-[1-[3-(4-chl... 1 0
Glycogen phosphorylase, liver form inhibitor TCMDC-135759 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437486 CHEMBL366703 Bioactive SureCN13451707
CFAMM00437485 CHEMBL367215 Bioactive SureCN13451755
CFAMM00437484 CHEMBL360731 Bioactive 1-(3,5-dichlorophenyl)-3-[[4-[4-(3-formylphenyl)phenyl]-1-methylpiperidin-4-yl]methyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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