CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1624
Family Name cAMP-dependent protein kinase type II-alpha regulatory subunit and cAMP-dependent protein kinase catalytic subunit alpha inhibitor N-[(4R)-4-[[4-(2-fluoro-6-hydroxy-3-methoxybenzoyl)benzoyl]amino]azepan-3-yl]pyridine-4-carboxamide;dihydrochloride family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00325754 Functional Category Bioactive
Superfamily C-X-C chemokine receptor type 2 and C-X-C chemokine receptor type 1 Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Smoothened homolog Inhibitor LDE225 Family 3 76
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Renin Inhibitor CP-305202 Family 9 30
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-[3... 1 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 1 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-[3-cy... 2 5
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 14
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 4 11
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
C-X-C chemokine receptor type 2 and C-X-C chemokine receptor t... 1 3
Beta-1 adrenergic receptor and Beta-3 adrenergic receptor liga... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 3 15
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 4 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 2 2
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325754 CHEMBL1202518 Bioactive N-[(4R)-4-[[4-(2-fluoro-6-hydroxy-3-methoxybenzoyl)benzoyl]amino]azepan-3-yl]pyridine-4-carboxamide;dihydrochloride
CFAMM00325757 CHEMBL1204096 Bioactive [(4R)-3-(pyridine-4-carbonylamino)azepan-4-yl] 4-(2-fluoro-6-hydroxy-3-methoxybenzoyl)benzoate;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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