CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16241
Family Name Pol polyprotein inhibitor (2R)-5-[(3S,5R)-3,5-dibenzyl-2-oxopyrrolidin-1-yl]-N-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-[(4-hydroxyphenyl)methyl]-4-oxopentanamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00437498 Functional Category Bioactive
Superfamily Pol polyprotein and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3076

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 20 35
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
Plasmepsin-2 Inhibitor KNI-10079 Family 19 8
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Genome polyprotein Inhibitor Acasp-glu-dif-ile-cha-cys-iqc-nle... 9 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 40 29
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 11 8
Pol polyprotein inhibitor (2S)-4-benzyl-1-[(2S,4R)-4-benzyl-2-... 10 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 4
E3 ubiquitin-protein ligase XIAP inhibitor N-METHYLALANYL-3-ME... 3 14
Pol polyprotein inhibitor MK-944a family 6 1
Pol polyprotein inhibitor (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-... 11 5
Pol polyprotein inhibitor 3-[[(3S,5R)-5-benzyl-1-[(2S,4R)-4-be... 4 0
Pol polyprotein inhibitor (2R,4S)-5-[(5R)-3-[(3-aminophenyl)me... 4 2
Pol polyprotein inhibitor AC1LADII family 12 1
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-5-benzyl-3-... 3 0
Pol polyprotein inhibitor L-689,502 family 17 2
A disintegrin and metalloproteinase with thrombospondin motifs... 2 2
Pol polyprotein inhibitor SDZ PRI 053 family 8 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 4
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5... 4 12
Pol polyprotein inhibitor AC1L9R8M family 4 1
Pol polyprotein inhibitor (3S,5R)-1-[(2S,4R)-6-amino-4-benzyl-... 1 0
Pol polyprotein inhibitor (2R,4S)-2-benzyl-5-[2-(tert-butylsul... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437500 CHEMBL361045 Bioactive (2R,4S)-2-benzyl-5-[(5R)-5-benzyl-3-[(3-hydroxyphenyl)methyl]-2-oxopyrrolidin-1-yl]-4-hydroxy-N-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide
CFAMM00437499 CHEMBL365219 Bioactive (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-[(4-hydroxyphenyl)methyl]-2-oxopyrrolidin-1-yl]-N-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-oxopentanamide
CFAMM00437498 CHEMBL361110 Bioactive (2R)-5-[(3S,5R)-3,5-dibenzyl-2-oxopyrrolidin-1-yl]-N-[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-[(4-hydroxyphenyl)methyl]-4-oxopentanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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