CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16245
Family Name 5-hydroxytryptamine receptor 6 ligand AGN-PC-075BWR family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00437504 Functional Category Bioactive
Superfamily Beta-lactamase and Integrin beta-3 Binder Superfamily 3
Class Class 1258

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
DNA Binder Primaquine Family 3 245
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Apricoxib family 8 77
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
5-hydroxytryptamine receptor 2A Ligand [2-(6-methoxy-indol-1-y... 2 10
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Prostaglandin G/H synthase 2 Inhibitor 5-methoxy-2-(4-(methyls... 3 12
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Tyrosine-protein kinase SYK and Low affinity immunoglobulin ep... 1 0
5-hydroxytryptamine receptor 6 ligand N-[3-[[(2R)-1-methylpyrr... 6 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Cannabinoid receptor 2 ligand AGN-PC-09M5M9 family 1 0
5-hydroxytryptamine receptor 6 ligand SureCN5502542 family 4 2
Prelamin-A/C inhibitor 1-[(3,4-dimethoxyphenethyl)amino]-3-(1H... 1 2
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Progesterone receptor and Androgen receptor ligand AGN-PC-04QD... 1 0
Glucocorticoid receptor ligand SureCN4194063 family 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor N-[4... 1 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(2,5-dimethoxypheny... 2 0
Vascular endothelial growth factor receptor 2 and Platelet-der... 1 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-(1-methyl-4... 14 12
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 1 0
Vascular endothelial growth factor receptor 2 ligand (4Z)-4-[(... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437504 CHEMBL361180 Bioactive AGN-PC-075BWR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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