CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1625
Family Name S-adenosylmethionine decarboxylase proenzyme inhibitor 6-[(E)-N-(diaminomethylideneamino)-C-methylcarbonimidoyl]pyridine-2-carboximidamide;dihydrochloride family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00325762 Functional Category Bioactive
Superfamily S-adenosylmethionine decarboxylase proenzyme inhibitor 6-[(E)-N-(diaminomethylideneamino)-C-methylcarbonimidoyl]pyridine-2-carboximidamide;dihydrochloride Superfamily
Class Class 3417

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Triprolidine Family 19 316
G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
Ribonucleoside-diphosphate reductase large subunit Inhibitor T... 1 1
Peptide deformylase, mitochondrial Inhibitor Hydroxy[3-(6-meth... 1 0
Metabotropic glutamate receptor 5 Ligand 2-methyl-6-(4-phenylb... 6 32
Cathepsin K Inhibitor 2-cyclohexylamino-pyridine-2-carbonitril... 1 2
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 9 24
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
D(3) dopamine receptor and D(4) dopamine receptor ligand (7S)-... 1 2
Microtubule-associated protein tau and Thyrotropin receptor li... 1 2
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 2


External ID

Functional Category

Molecule Name

CFAMM00325762 CHEMBL1202792 Bioactive 6-[(E)-N-(diaminomethylideneamino)-C-methylcarbonimidoyl]pyridine-2-carboximidamide;dihydrochloride
CFAMM00325766 CHEMBL151197 Bioactive [2,2'-Bipyridine]-6,6'-dicarboximidamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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