CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1626
Family Name Type-1 angiotensin II receptor and Type-2 angiotensin II receptor ligand AGN-PC-088UH2 family
No. of Seeds 16 No. of Other Members 30
Family Centroid CFAMM00325795 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-2 angiotensin II receptor Binder Superfamily
Class Class 3418

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Losartan Family 3 90
Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Type-1 angiotensin II receptor ligand SureCN9527437 family 2 34
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 12 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 6
Type-1 angiotensin II receptor ligand 1-butyl-5-[4-[2-(2H-tetr... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 35 14
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 8 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 0
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Proto-oncogene c-Fos and Transcription factor AP-1 inhibitor A... 1 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325796 CHEMBL1202855 Bioactive AGN-PC-088UH3
CFAMM00325810 CHEMBL92258 Bioactive 4-[2-methoxyethyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-2-methylpyrimidine-5-carboxylic acid
CFAMM00325795 CHEMBL1202854 Bioactive AGN-PC-088UH2
CFAMM00325773 CHEMBL49410 Bioactive 4-[propyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyrimidine-5-carboxylic acid
CFAMM00325815 CHEMBL316062 Bioactive SureCN9590649
CFAMM00325800 CHEMBL1202852 Bioactive 2-ethyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methylamino]pyrimidine-5-carboxylic acid;hydrochloride
CFAMM00325791 CHEMBL1237156 Bioactive 4-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-2-methylpyrimidine-5-carboxylic acid;hydrochloride
CFAMM00325770 CHEMBL315148 Bioactive SureCN9589359
CFAMM00325798 CHEMBL1202857 Bioactive SureCN9589520
CFAMM00325790 CHEMBL1237157 Bioactive 4-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]pyrimidine-5-carboxylic acid;hydrochloride
CFAMM00325804 CHEMBL327645 Bioactive SureCN9592048
CFAMM00325769 CHEMBL333534 Bioactive 141872-46-0
CFAMM00325782 CHEMBL88231 Bioactive SureCN9590490
CFAMM00325811 CHEMBL90886 Bioactive 4-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-2-methylsulfanylpyrimidine-5-carboxylic acid
CFAMM00325775 CHEMBL421473 Bioactive SureCN9590851
CFAMM00325781 CHEMBL124772 Bioactive 4-[butyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-2-methylpyrimidine-5-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26239 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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