CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16287
Family Name Coagulation factor X and Coagulation factor IX inhibitor 5-amidinoindole 20 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00283387 Functional Category Bioactive
Superfamily Coagulation factor X and Coagulation factor IX Binder Superfamily 4
Class Class 716

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Prothrombin Inhibitor Dabigatran Family 7 182
Growth hormone receptor Ligand EP-51216 Family 34 390
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
NS5A protein Inhibitor Bms 790052 Family 5 9
BIBT986 family 7 96
Eluxadoline family 4 85
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Insulin-like growth factor 1 receptor ligand AGN-PC-09QGLU family 3 1
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Coagulation factor X inhibitor SureCN8289965 family 4 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Type-1 angiotensin II receptor ligand 7-methyl-N-(2-phenylethy... 2 10
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 7 15
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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