CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16289
Family Name 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 3B ligand 2-[2-(4-methylpiperazin-1-yl)-4-phenylquinolin-3-yl]ethanol family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00437635 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine receptor 3A Binder Superfamily 6
Class Class 2845

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Tyrosine kinase Inhibitor PKI166 Family 17 198
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Histamine H4 receptor Ligand A-943931 Family 14 11
Amine oxidase [flavin-containing] A Inhibitor 3-benzyl-n-(2-mo... 2 3
Androgen receptor Ligand 11-methyl-6,11-dihydro-5h-benzo[a]car... 7 9
5-hydroxytryptamine receptor 3A and D(2) dopamine receptor Lig... 1 0
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 4
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 3 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 2 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 8


External ID

Functional Category

Molecule Name

CFAMM00437636 CHEMBL42912 Bioactive AGN-PC-073MEY
CFAMM00437635 CHEMBL39364 Bioactive 2-[2-(4-methylpiperazin-1-yl)-4-phenylquinolin-3-yl]ethanol
CFAMM00437639 CHEMBL364895 Bioactive [3-(hydroxymethyl)-2-(4-methylpiperazin-1-yl)quinolin-4-yl]methanol
CFAMM00437638 CHEMBL41841 Bioactive AGN-PC-073MO5

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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