CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16299
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor (11S)-3,10-dibromo-8-chloro-11-(1-methylsulfonylpiperidin-4-yl)-11H-benzo[1,2]cyclohepta[2,4-b]pyridine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00437676 Functional Category Bioactive
Superfamily Farnesyltransferase beta subunit, putative Inhibitor Lonafarnib Superfamily
Class Class 891

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Farnesyltransferase beta subunit, putative Inhibitor Lonafarni... 36 87


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437676 CHEMBL365463 Bioactive (11S)-3,10-dibromo-8-chloro-11-(1-methylsulfonylpiperidin-4-yl)-11H-benzo[1,2]cyclohepta[2,4-b]pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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