CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1631
Family Name Kappa-type opioid receptor ligand 2-(1-benzofuran-4-yl)-N-methyl-N-[(5S,7R,8R)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide;hydrochloride family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00325848 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Binder Superfamily 3
Class Class 769

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-317920 Family 9 240
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
Melatonin receptor type 1A and Melatonin receptor type 1B Liga... 33 98
Endothelin-1 receptor and Endothelin B receptor ligand (2R,3R,... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325849 CHEMBL539246 Bioactive 2-(1-benzofuran-4-yl)-N-methyl-N-[(7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide;hydrochloride
CFAMM00325848 CHEMBL1202931 Bioactive 2-(1-benzofuran-4-yl)-N-methyl-N-[(5S,7R,8R)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide;hydrochloride
CFAMM00325847 CHEMBL537616 Bioactive 2-(1-benzofuran-4-yl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide;hydrobromide
CFAMM00325846 CHEMBL318859 Bioactive ENADOLINE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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