CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16311
Family Name Plasmepsin-1 and Plasmepsin-2 inhibitor N-[(2S,3S)-5-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-5-oxo-1-[(4-phenylphenyl)methoxy]pentan-2-yl]-2,4,6-trifluorobenzamide family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00320514 Functional Category Bioactive
Superfamily Plasmepsin-2 and Plasmepsin-1 Binder Superfamily
Class Class 923

Cousin Family NamesSeedsMembers
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(4-me... 2 9
Plasmepsin-1 and Plasmepsin-2 inhibitor Statine-like inhibitor... 1 6
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 1 2
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
Cathepsin B and Cathepsin L1 inhibitor 3-[[(2R)-2-cyano-2-[[(2... 3 4
Plasmepsin-1 and Plasmepsin-2 inhibitor N-[(2S,3S)-5-[[(2S)-1-... 1 2
Beta-secretase 1 and Cathepsin E inhibitor 1-N-[(1R,2S)-3-(3,5... 3 8
Beta-secretase 1 inhibitor 1-N-[(2S,3R)-1-(3,5-difluorophenyl)... 8 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437718 CHEMBL371082 Bioactive N-[(2S,3S)-5-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-5-oxo-1-[(4-thiophen-3-ylphenyl)methoxy]pentan-2-yl]-2,4,6-trifluorobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27283 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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