CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16320
Family Name Angiotensin-converting enzyme and Angiotensin-converting enzyme 2 inhibitor (2R)-1-[2-(3-benzamido-2-oxo-4-phenylbutoxy)acetyl]pyrrolidine-2-carboxylic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00437758 Functional Category Bioactive
Superfamily Angiotensin-converting enzyme and Caspase-1 Binder Superfamily
Class Class 506

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme inhibitor Phosphonate-containing... 7 41
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Dopamine reuptake Inhibitor Amineptine Family 2 5
Penicillin-binding protein 1B Inhibitor N-benzoyl-d-alanine Fa... 1 40
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor L-709780 Family 9 10
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Trifunctional purine biosynthetic protein adenosine-3 Inhibito... 2 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Inhibit... 5 23
Cathepsin S Inhibitor N-(1-oxobutan-2-yl)-3-(trifluoromethyl)b... 2 10
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Angiotensin-converting enzyme inhibitor (S)-1-((S)-5-benzamido... 5 2
Chymotrypsin-like elastase family member 2A and Chymotrypsinog... 2 18
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7285564... 1 2
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Angiotensin-converting enzyme and Histone-lysine N-methyltrans... 1 19
Chymase and Chymotrypsinogen B inhibitor AGN-PC-075LTI family 2 3
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437758 CHEMBL366420 Bioactive (2R)-1-[2-(3-benzamido-2-oxo-4-phenylbutoxy)acetyl]pyrrolidine-2-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27284 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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